When is Enough, Enough?

Macbeth has gone off the deep end. He has killed his best friend Banqou and the innocent Mcduff family without so much as pausing to think about his actions. His thirst for power is unmeasurable, as I believe Macbeth is now willing to do anything and everything to keep the crown. At this point in the story, he can't undo what he has done. There's no way of going back and un-killing anyone, so he can't decide to quit because he already too involved. He must keep the killing of Duncan and everyone else undercover because there's no way out of his situation without himself being executed for what he's done. Will the murders ever stop though? The only solutions out of the mess he has entangled himself into is to either run far, far away, kill himself, or keep murdering anybody close to him so he can remain king. I'm not sure if he'll ever reach a point where he can be king without having someone else he needs to kill. Enough may never be enough for Macbeth. Lady Macbeth, on the other hand, has almost reached her breaking point. She is about to call it quits. Her heavy conscience doesn't let her sleep and she is beginning to go insane. I'm intrigued to see how she will back out of this murderous disaster. Is there any other option besides suicide for her?